Supporting Woment with Breast Cancer to Prepare for Treatment (The Prepare Study)
Aims: To measure the impact of a mindfulness intervention instituted prior to surgery on patient anxiety for newly diagnosed breast cancer patients.
Diagnosis: Breast Cancer- Participants must enroll prior to breast surgery
Principal Investigator: Katherine Yao, MD
IRB Approval Number: EH20-134
Sponsor: Myra Rubenstein Weis Foundation and John Wayne Cancer Foundation
Contact: Interested patients may contact Sandra Simovic at 847.570.4227, ssimovic@northshore.org
Open to Enrollment: Yes
PROMPT-BC Patient Reported Observations on Medical Procedure Timeliness – Breast Cancer
Aims: To understand patient’s perspectives on the timeliness of the breast cancer diagnostic process and time to first treatment thru qualitative interviews.
Diagnosis: Breast Cancer
Principal Investigator: Katherine Yao, MD
IRB Approval Number: EH21-349
Sponsor: NorthShore University Healthsystem
Contact: Interested patients may contact Sandra Simovic at 847.570.4227, ssimovic@northshore.org
Open to Enrollment: Yes – Spanish speaking patients only
S2007: AS2007, “A Phase II Trial of Sacituzumab Govitecan for Patients with HER2-Negative Breast Cancer and Brain Metastases
Aims: The purpose of this study is to see if the drug Sacituzumab govitecan will help women with breast cancer whose cancer has spread to their brain.
Diagnosis: Breast Cancer
Principal Investigator: Poornima Saha, MD
IRB Approval Number: EH22-225
Sponsor: Southwest Oncology Group
Contact: Interested patients should contact research nurse Michele Britto, RN at 847.570.2109
Open to Enrollment: Yes
EA1181: The CompassHER2 Trials (COMprehensive us of Pathological Response ASSessment to optimize therapy in HER2-positive breast cancer): CompassHER2 Residual Disease (RD), a double-blinded, phase III randomized trial of T-DM1 and placebo compared with T-DM1 adn tucatinib
Aims: The purpose is to see if patients who have no cancer after intial therapy and surgery need additional chemotherapy or would targeted treatments be enough.
Diagnosis: Breast cancer
Principal Investigator: Poornima Saha, MD
IRB Approval Number: EH21-154
Sponsor: Alliance for Clinical Trials in Oncology
Contact: Interested patients should contact research nurse Michele Britto, RN at 847.570.2109
Open to Enrollment: Yes
A011801: (CompassHERCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response.
Aims: The purpose is to see if adding tucabinib to the standard treatment of T-DM1 is better than T-DM1 alone in preventing your cancer from returning.
Diagnosis: Breast cancer
Principal Investigator: Poornima Saha, MD
IRB Approval Number: EH21-013
Sponsor: ECOG-ACRIN
Contact: Interested patients should contact research nurse Michele Britto, RN at 847.570.2109
Open to Enrollment: Yes
A Prospective, Multicenter Investigation of the da Vinci® Xi™ Surgical System in Nipple Sparing Mastectomy (NSM) Procedures
Aims: To evaluate the safety and effectiveness of the Vinci® Xi™ Surgical System, instruments and accessories in NSM procedures performed for prophylaxis.
Diagnosis: High Risk for Breast Cancer
Principal Investigator: Katharine Kopkash, MD
IRB Approval Number: EH19-074
Sponsor: NorthShore University Healthsystem
Contact: Interested patients may contact Sarah Rabbitt, RN, CCRP at 847.570.1681, srabbitt@northshore.org
Open to Enrollment: Yes
A Prospective, Multicenter Randomized Controlled Trial (RCT) of the da Vinci® SP™ Surgical System vs Open Surgery in Nipple Sparing Mastectomy (NSM) Procedures
Aims: This study is a prospective, two-arm, multi-center, randomized controlled clinical investigation between RSNM and open NSM. This study evaluates the safety and effectiveness of the da Vinci SP Surgical System compared to Open NSM in Nipple Sparing Mastectomy procedures.
Diagnosis: DCIS and/or invasive breast carcinoma clinical stage Tis, T1, T2 with N0
Principal Investigator: Katharine Kopkash, MD
IRB Approval Number: EH23-039
Sponsor: Intuitive Surgical
Contact: Interested patients may contact Anne Jankowski at 847.570.1512, AJankowski@northshore.org
Open to Enrollment: Yes